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Treatment Options Improved and Effective Drug Developed for SCI

A new study has shed light on the link between the neurological damage caused by a spinal cord injury, spontaneous motor function recovery and long-term motor deficits may lead to better treatments.

Researchers studied how laboratory rats recovered motor function four months after researchers simulated a C-6 partial spinal cord injury. Scientists found extensive kinetic, anatomical and electrophysiological data demonstrating how the rats compensated for their permanent loss of motor function.

According to Dr. W. Dalton Dietrich, III, PhD, who is the scientific director of the Miami Project to Cure Paralysis at the University of Miami Leonard M. Miller School of Medicine, “this paper is important to the spinal cord injury field because it provides a comprehensive assessment of motor performance up to four months after cervical spinal cord injury, identifying progressive sensorimotor compensatory processes that indicate new targets for therapeutic strategies to promote recovery and repair.”

Effective Drug

On a separate note, researchers at Ohio State University have tested a new drug on laboratory mice that helped improve the animals’ limb movement. According to, the drug used in this case crossed the blood-brain barrier, did not increase pain and had no toxic effects.

In their study, researchers looked at a small molecule called oligodendrocytes. The molecule prevents the death of cells by surrounding and protecting long projections of a nerve cell called axons, by wrapping them in myelin which is an electrically insulating material that forms a layer (called the myelin sheath) that helps increase the speed at which electrical impulses (the orders sent by the brain to the spinal cord) propagate.

A spinal cord injury causes a protein named P75 to kill oligodendrocytes, whose death in turn causes the axons they support to degenerate, preventing the successful reception of the electrical impulses (orders) that the brain sends to the spinal cord. The experimental drug is the first to be developed with a specific target as a potential therapy for spinal cord injury. It has been named is LM11A-31 and was developed at Stanford University by Dr. Frank Longo, Professor of Neurology and Neurological Services.

The Lawyers of Greenberg Stone and Urbano Can Help

If you or a loved one have suffered a spinal cord injury as a result of a car accident, a motorcycle accident, a tractor-trailer accident, an accident at an amusement park or any other kind of accident, you should immediately contact a law firm experienced in handling these cases. Throughout the years, the Miami Dade County Car Accidents Law Offices of Greenberg Stone and Urbano have represented victims of spinal cord injuries resulting from car accidents, motorcycle accidents, tractor-trailer accidents, accidents at an amusement park or any other kind of accident caused by someone else’s negligence recover the compensation that may be owed to them.

Our attorneys have more than 100 years of combined experience helping accident victims. Visit our website to learn more about our firm and contact us today to schedule a free consultation.

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