Published on:

Scientists Try to Create “One Size Fits All” Drug to Treat Brain

Researchers from Northwestern University Feinberg School of Medicine have created a new drug that could treat the neuro-inflammation suffered by the human brain as a result of Alzheimer’s, Parkinson’s, Multiple Sclerosis and traumatic brain injuries.

According to, all the conditions mentioned above have separate treatments and therapies to deal with the neuro-inflammation of the brain. Neuro-inflammation is in reality a response of the brain to the conditions created by these illnesses and accidents. It is caused by the release in large quantities of a molecule called cytokine. The drug developed at Northwestern binds onto cytokine and decreases its numbers.

Saving the Neurons

According to Dr. Martin Watterson, professor of molecular pharmacology and biological chemistry at Feinberg School of Medicine, the challenge was producing a molecule that could be safely delivered to the brain during the early stages of the disease or injury, a molecule that would tone down the inflammation without toning down the immune response that was causing the inflammation. Tests on mice genetically engineered to develop Alzheimer’s revealed that 11 months after being administered the drug, their neuro-inflammation had decreased and their brain synapsis were working normally.

A common indicator of Alzheimer’s progression is the development of beta amyloid plaques in the brain, which is what current treatments target. The new drug developed at Northwestern targets the increase of the cell-signaling molecule cytokine, which is a precursor to the development of neurodegenerative disorders.

According to Dr. Watterson, “the neurons and glia work together in the nervous system, and when the neurons get stressed, they send signals out telling the glia, ‘I’m being stressed, I’m being attacked”. “The glia then releases cytokine and other molecules [to attack the stressors]. What happens with disease progression is this cycle gets out of control, causing innocent bystander effect, meaning that the synapses in the brain are attacked as well.”

If the cycle is allowed to become uncontrollable and more cytokine is produced, more damage is caused to the neurons. If the neurons are stressed for too long, they wither and die. Consequently, according to Professor Watterson, this period of time is the target window for taking the drug because it allows doctors to save the neurons.

The Lawyers of Greenberg Stone and Urbano Can Help

With over 67 years of combined experience, the lawyers at Greenberg Stone and Urbano can help victims that have suffered any kind of traumatic brain injury as a result of an accident recover the funds they need for their rehabilitation. These funds may include money for the expensive treatments mentioned in these posts, for rehabilitation therapy, for your pain and suffering and for lost wages. Throughout the years, the Miami Dade County Traumatic Brain Injury Law Offices of Greenberg Stone and Urbano have represented many clients that have suffered traumatic brain injuries.

If you or a loved one have suffered a traumatic brain injury as a result of a car accident, a truck accident, an amusement park accident or as a result of any other kind of accident, you should immediately contact a law firm experienced in handling these cases. Visit our website to learn more about our firm and contact us today for a free consultation.

Contact Information